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This page was prepared by E. Stankowski RN **************************************************** Novolog 70/30, What is Novolog 70/30, Centerwatch.com:"Novolog Mix is an insulin analog premix containing 30% rapid-acting insulin aspart and 70% that has been modified into a long-acting formulation. It has been approved in a subcutaneous injection formulation, for the control of hyperglycemia. Hyperglycemia is an abnormally increased content of sugar in the blood."Thomson CenterWatch 22 Thomson Place, 47F1 Boston, MA 02210-1212 Phone: (617) 856-5900 or Fax: (617) 856-5901 E-mail: visitor@centerwatch.com or cw.mailroom@centerwatch.com http://www.centerwatch.com/patient/drugs/dru729.html **************************************************** Novolog 70/30, Mechanism of action, Drugs.com:"The primary activity of NovoLog Mix 70/30 is the regulation of glucose metabolism. Insulins, including NovoLog Mix 70/30, exert their specific action through binding to insulin receptors. Insulin binding activates mechanisms to lower blood glucose by facilitating cellular uptake of glucose into skeletal muscle and fat, simultaneously inhibiting the output of glucose from the liver."Hampstead Trust ATTN: DRUGS.COM c/o Network Solutions P.O. Box 447 Herndon, VA 20172-0447 Phone: (570) 708-8780 E-mail: contact @ drugs.com http://www.drugs.com/PDR/NovoLog_Mix_70_30.html **************************************************** Novolog 70/30, What should my health care professional know before I receive Insulin Aspart; Insulin Aspart Protamine? Drugdigest.org:"They need to know if you have any of these conditions:•adrenal or pituitary gland problems, •diarrhea, •fever or infection, •injury or trauma, •kidney disease, •liver disease, •nausea, vomiting, •recent surgery, •thyroid disease, •pregnant or trying to get pregnant, •breast-feeding, •an unusual or allergic reaction to insulin, metacresol, other medicines, foods, dyes, or preservatives."DrugDigest Expresscripts.com 521 Alton Rd #208, Miami Beach, FL 33140, US E-mail: questions@express-scripts.com http://www.drugdigest.org/DD/DVH/Uses/0,3915,8447|Novolog%2B70%257E22%257E30,00.html#precautions **************************************************** Novolog 70/30 Flexpen, Onset of Action Directions, Drugstore.com:"Follow the directions for using this medicine provided by your doctor. THIS INSULIN BEGINS LOWERING BLOOD SUGAR RAPIDLY, within minutes. The peak effect of this insulin occurs 1 to 4 hours after the dose. The effects last for up to 24 hours."Drugstore.com 407 Heron Drive Swedesboro, NJ 08085-9810 Phone: (1-800) 378-4786 E-mail: aboutrx@drugstore.com http://www.drugstore.com/qxn00169369619_333181_sespider/novolog_mix_7030_flexpen/novolog_mix_7030_flexpen.htm **************************************************** Insulin aspart-insulin aspart protamine, What happens if I overdose? Healthyahoo.com:"Seek emergency medical attention if an overdose is suspected. Symptoms of an insulin overdose reflect very low blood sugar levels and include headache, irregular heartbeat, increased heart rate or pulse, sweating, tremor, nausea, increased hunger, and anxiety."Health Yahoo.com Yahoo! Inc. 701 First Avenue Sunnyvale, CA, 94089 (US) http://health.yahoo.com/drug/d04839a1#d04839a1-overdose **************************************************** Insulin, Use of this medicine in Children and Teens, Mayoclinic.com:"Children are especially sensitive to the effects of insulin before puberty (the time when sexual changes occur). Therefore, low blood sugar may be especially likely to occur.Use in teenagers is similar to use in older age groups. The insulin need may be higher during puberty and lower after puberty."Mayo Foundation for Medical Education and Research 200 1st St. S.W. Rochester, MN 55905 E-mail: comments@mayoclinic.com http://www.mayoclinic.com/invoke.cfm?objectid=0DAB2863-5831-4924-875096935276AED7#Before%20Using%20This%20Medicine **************************************************** INSULIN ASPART PROTAMINE/INSULIN ASPART - INJECTABLE, MISSED DOSE, Medicinenet.com:"It is very important to follow your insulin regimen exactly. Do not miss any doses of insulin. Discuss specific instructions with your doctor now, in case you miss a dose of insulin in the future."MedicineNet, Inc. 903 Calle Amanecer, Suite 300 San Clemente, CA 92673 Phone: (949) 940-6500 or Fax: (949) 940-1094 E-mail:smartservice@medicinenet.com http://www.medicinenet.com/insulin_aspart_protamineinsulin_aspart-inject/page3.htm#MissedDose **************************************************** Insulin, Precautions while using this medicine, Medlineplus:"It is very important to follow carefully any instructions from your health care team about:Alcohol—Drinking alcohol may cause severe low blood sugar. Discuss this with your health care team. Tobacco—If you have been smoking for a long time and suddenly stop, your dosage of insulin may need to be reduced. If you decide to quit, tell your doctor first."National Library of Medicine 8600 Rockville Pike Bethesda, Maryland 20894 Phone: (301) 496-6308 Fax: (301) 496-4450 E-mail: custserv@nlm.nih.gov http://www.nlm.nih.gov/medlineplus/druginfo/uspdi/203298.html#SXX18 **************************************************** Novolog 70/30, A typical schedule with NovoLog® Mix 70/30, Novologmix70-30.com:"NovoLog® Mix 70/30 is usually taken twice daily. A typical starting dose could be 6 units at breakfast and 6 units at dinner.1Your doctor will work with you to find the correct dosage for you. When you begin taking NovoLog® Mix 70/30 or any insulin, your doctor may have to adjust how much insulin you need based on your blood glucose levels before you eat."Customer Care Novo Nordisk Inc. 100 College Road West Princeton, NJ 08540 Phone: 1-800-727-6500 E-mail Contact Form:http://www.novonordisk-us.com/documents/form_editor/document/ContactUs.asp http://www.novologmix70-30.com/consumer/why/default.asp **************************************************** Novolog 70/30, Possible Side Effects, Rxlist.com:"Eczema, itching. Hypoglycemia (low blood sugar) and hypokalemia (low potassium) are possible with use of all insulin. Fluid retention. Hypoglycemia (low blood sugar) and hypokalemia (low potassium) are possible with use of all insulin. Other possibilities with human insulin may include itching, rash, and fluid retention."RxList - The Internet Drug Index: Searchable Drug Database RxList LLC 16092 San Dieguito Road Rancho Sante Fe, CA 92067 Phone: (707) 747-0985 or Fax: (708) 575-8638 E-mail: info@rxlist.com http://www.rxlist.com/cgi/pharmclips2.cgi?keyword=%20Novolog%20Mix%2070%2030%AE#effects **************************************************** ************************************************************************************************************
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