Possible side effects of Quazepam (Doral):rxlist:"If you experience any of the following serious side effects, stop taking quazepam and seek emergency medical attention: an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, face, or tongue; or hives); sores in your mouth or throat; yellowing of the skin or eyes; a rash; hallucinations or severe confusion; or changes in your vision. Other, less serious side effects may be more likely to occur. Continue to take quazepam and talk to your doctor if you experience drowsiness, dizziness, or clumsiness; depression; nausea, vomiting, diarrhea, or constipation; difficulty urinating; vivid dreams; headache; dry mouth; decreased sex drive; or changes in behavior. Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome"
http://rxlist.com/frame/display.cgi?drug=DORAL

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Important information you should know about Quazepam (Doral):drugs.com:"Use caution when driving, operating machinery, or performing other hazardous activities. Quazepam will cause drowsiness and may cause dizziness. If you experience drowsiness or dizziness, avoid these activities. Take quazepam only when you are ready to get into bed. Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking quazepam. Do not stop taking quazepam suddenly if you have been taking it for several weeks. This may cause withdrawal symptoms and make you uncomfortable. Talk to your doctor if you need to stop treatment with quazepam"
http://www.drugs.com/xq/cfm/pageID_0/htm_D00917A1.htm/bn_quazepam/qx/index.htm

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Action and Kinetics of Quazepam (Doral):nursespdr:"Improves sleep induction time, duration of sleep, number of nocturnal awakenings, occurrence of early morning awakening, and sleep quality without producing an effect on REM sleep. Hangover effects are minimal. Peak plasma levels: 2 hr. Quazepam and two of its metabolites (2-oxoquazepam and N-desalkyl-2-oxoquazepam) are active on the CNS. t1/2, quazepam and 2-oxoquazepam: 39 hr; t1/2, N-desalkyl-2-oxoquazepam: 73 hr. Significantly (95%) bound to plasma protein"
http://www.nursespdr.com/members/database/archives/quazepam.html

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Precautions to be aware of while taking Quazepam (Doral):healthandage.com:"Check medicines with healthcare provider. This medicine may not mix well with other medicines, especially with certain antibiotics. This medicine may be habit-forming with long-term use. If you are 65 or older, you may have more side effects. You could feel sleepy and shaky. You may not be alert. Avoid driving, doing other tasks or activities until you see how this medicine affects you. Avoid alcohol (includes wine, beer, and liquor) and other medicines and herbs that slow your actions and reactions. This includes sedatives, tranquilizers, mood stabilizers, or pain medicine. Talk with healthcare provider. Tell healthcare provider if you have lung disease. You may be more sensitive to this medicine. Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, throat; or any other symptoms involved. Do not use in pregnancy and do not get pregnant. Use birth control that you can trust while taking this medicine. Do not use if you are breast-feeding."
http://www.healthandage.com/html/res/com/ConsDrugs/Quazepamcd.html

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Quazepam (Doral) pregnancy precautions and drug interactions::"If Doral is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Doral with the following: Antihistamines such as Benadryl Antiseizure medications such as Dilantin and Tegretol Mood-altering medications such as Thorazine and Clozaril Other central nervous system depressants such as Xanax and Valium Do not drink alcohol while taking Doral; it can increase the drug's effects. Because Doral may cause harm to the unborn child, it should not be taken during pregnancy. If you want to have a baby, tell your doctor, and plan to discontinue taking Doral before getting pregnant. Babies whose mothers are taking Doral at the time of birth may experience withdrawal symptoms from the drug. Such babies may be "floppy" (flaccid) instead of having normal muscle tone. Since Doral does appear in breast milk, you should not take this medication if you are nursing a baby"
http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/dor1147.shtml

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Quazepam (Doral) food, drug and disease interactions:wholehealthmd:"Drug Interactions Other drugs may interact with quazepam. Consult your doctor for specific advice if you are taking any drugs that depress the central nervous system; these include antihistamines, antidepressants or other psychiatric medications, barbiturates, sedatives, cough medicines, decongestants, and painkillers. Be sure your doctor knows about any over-the-counter medication you may take. Food Interactions None reported. Disease Interactions Caution is advised when taking quazepam. Consult your doctor if you have a history of alcohol or drug abuse, stroke or other brain disease, any chronic lung disease, hyperactivity, depression or other mental illness, myasthenia gravis, sleep apnea, epilepsy, porphyria, kidney disease, or liver disease."
http://www.wholehealthmd.com/refshelf/drugs_view/1,1524,537,00.html

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How should you take Quazepam (Doral)?:healthsquare:"Take Doral exactly as prescribed by your doctor--one dose per day, at bedtime. Keep in touch with your doctor; if you respond very well, it may be possible to cut your dosage in half after the first few nights. The older or more run-down you are, the more desirable it is to try for this early dosage reduction. If you have been taking Doral regularly for 6 weeks or so, you may experience withdrawal symptoms if you stop suddenly, or even if you reduce the dosage without specific instructions on how to do it. Always follow your doctor's advice for tapering off gradually from Doral. If you miss a dose...Take this medication only if needed. Storage instructions...Store at room temperature, away from moisture"
http://www.healthsquare.com/newrx/dor1147.htm

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Special precautions while taking Quazepam (Doral):healthtrust:"Check medicines with healthcare provider. This medicine may not mix well with other medicines, especially with certain antibiotics. This medicine may be habit-forming with long-term use. If you are 65 or older, you may have more side effects. You could feel sleepy and shaky. You may not be alert. Avoid driving, doing other tasks or hobbies until you see how this medicine affects you. Avoid alcohol (includes wine, beer, and liquor) and other medicines that slow your actions and reactions. This includes sedatives, tranquilizers, mood stabilizers, or pain medicine. Talk with healthcare provider. Tell healthcare provider if you have lung disease. You may be more sensitive to this medicine. Tell healthcare provider if you are allergic to any medicine. Make sure to tell about the allergy and how it affected you. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, throat; or any other symptoms involved. Do not use in pregnancy and do not get pregnant. Use birth control that you can trust while taking this medicine. Do not use if you are breast-feeding."
http://www.healthtrust.com/intmed/Access2Cons2/ConsDrugs/Quazepamcd.shtml

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Quazepam (Doral) contraindications and dosage information:edoc:"Contra-Indications: Known hypersensitivities to benzodiazepenes. Patients with narrow angle glaucoma. In patients with established or suspected sleep apnoea. Dosage: Management of overdose: Symptoms: Somnolence, confusion, coma, respiratory and cardiovascular depression, hypotension. Kinetics: t1/2 equals 39 hours, and has 2 active metabolites with t1/2 39hours and 72 hours. (long acting benzodiazepene) Rx: Symptomatic and supportive. Dose: RANGE: 15mg - 30mg at night. ADULTS: Usual dose is 15mg at night, and if necessary increased to 30mg at night. ELDERLY: It is advisable to initiate treatment at 7.5mg. NIGHT BEFORE SURGERY: 30mg at night"
http://www.edoc.co.za/medilink/actives/889.html

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Quazepam (Doral) other important information and precautions:4therapy.com:"Do not take Doral (quazepam) if you have narrow-angle glaucoma, since this medication may worsen this condition. Before taking this medication, tell your doctor or therapist if you...have kidney disease have liver disease have asthma, bronchitis, emphysema, or another respiratory disease are depressed or have suicidal thoughts You may not be able to take Doral (quazepam), or you may require a lower dose or special monitoring during treatment, if you have any of these conditions. This drug should not be given to anyone under twelve years of age, or to anyone who has sleep apnea. In addition to the information listed above, there may be other important issues or precautions related to this medication. For further information, you can ask your prescribing doctor or therapist."
http://www.4therapy.com/consumer/medications/item.php?uniqueid=100



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