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Clarithromycin, Biaxin, Indications For Usage, biaxinxl.com:"Clarithromycin is contraindicated in patients taking cisapride, pimozide, astemizole, or terfenadine due to the potential for cardiac arrhythmias when taken in combination; and in patients with a known hypersensitivity to clarithromycin or any other macrolide antibiotic. Clarithromycin may elevate serum digoxin concentrations. Serum digoxin concentrations should be carefully monitored while digoxin and clarithromycin are taken concomitantly. Clarithromycin should not be used in pregnant women except in circumstances for which no alternative therapy is appropriate."
http://www.biaxinxl.com/bx/xl/bxx002.htm

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Biaxin® BID tablets, Lung Diseases Treated with this Drug, Canadian Lung Association:"bronchitis middle ear infections pharyngitis pneumonia respiratory tract infections sinus infections sinusitis sore throat tonsilitis upper respiratory tract infections."
http://www.lung.ca/drugs/pages/62.html

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Clarithromycin (Biaxin), CenterWatch Newly Approved Drug Therapies Listing:"Clinical trial results demonstrated that clarithomycin is effective in reducing the risk of developing disseminated MAC disease in subjects with advanced AIDS. In a randomized, double-blind, placebo-controlled study conducted in the United States and Europe, subjects with advanced AIDS (CD4 cell counts less than or equal to 100 cells) and a negative MAC blood culture received either clarithromycin 500 mg twice daily (n=341) or placebo twice daily (n=341). The median duration of treatment with clarithromycin was 10.6 months, as compared to a median duration of 8.2 months for the placebo-treated group. The risk of developing disseminated MAC was reduced by 69 percent in the clarithromycin-treated subject group, compared to placebo."
CenterWatch
22 Thomson Place, 36T1 Boston, MA 02210-1212
Phone: 617-856-5900 Fax: 617-856-5901
http://www.centerwatch.com/patient/drugs/dru28.html

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Biaxin, Special warnings about this medication, gettingwell.com:"If you have severe kidney disease, the doctor may need to prescribe a smaller dose of Biaxin. Make sure the doctor is aware of any kidney problems you may have. Like other antibiotics, Biaxin may cause a potentially life-threatening form of diarrhea that signals a condition called pseudomembranous colitis (inflammation of the large intestine). Mild diarrhea, a fairly common Biaxin side effect, may disappear as your body gets used to the drug. However, if Biaxin gives you prolonged or severe diarrhea, stop taking the drug and call your doctor immediately."
http://www.gettingwell.com/drug_info/rxdrugprofiles/drugs/bia1055.shtml

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Biaxin, Possible food and drug interactions, Heatlhsquare.com:"when taking this medication. If Biaxin is taken with certain other drugs, the effects of either can be increased, decreased, or altered. It is especially important to check with your doctor before combining Biaxin with the following: Alprazolam (Xanax) Blood thinners such as Coumadin Bromocriptine (Parlodel) Carbamazepine (Tegretol) Cholesterol-lowering drugs such as Mevacor and Zocor Cilostazol (Pletal) Cyclosporine (Sandimmune, Neoral) Digoxin (Lanoxin) Disopyramide (Norpace) Ergot-based migraine drugs such as Cafergot, DHE, Sansert, and Wigraine Fluconazole (Diflucan) Hexobarbital Methylprednisolone (Medrol) Midazolam (Versed) Phenytoin (Dilantin) Quinidine (Quinidex) Pimozide (Orap) Rifabutin (Mycobutin) Ritonavir (Norvir) Sildenafil (Viagra) Tacrolimus (Prograf) Theophylline (Slo-Phyllin, Theo-Dur, others) Triazolam (Halcion) Valproate (Depakene, Depakote) Zidovudine (Retrovir)."
New Media Systems, LLC
Jefferson Square Building 621 Shrewsbury Avenue
Shrewsbury, NJ 07702
Email rcollado@nmspartners.com Phone (732) 212-9191 Fax (732) 212-1260
http://www.healthsquare.com/newrx/bia1055.htm

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Clarithromycin, HIVDent.org:"A Commonly Used Medication for HIV & AIDS Patients. Macrolide antibiotic Indication: Treatment of MAI or DMAC; strep pharyngitis, sinusitis, bronchitis, community-acquired pneumonias."
http://www.hivdent.org/drugs/clarithromycin.htm

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Clarithromycin (Biaxin), Why Do People With Hiv Take Clarithromycin?The New Mexico Aids Info Net:"Clarithromycin is used for mild or moderate bacterial infections. It works against several different bacteria, especially chlamydia, hemophilus and streptococcus. These bacteria can infect the skin, nose, throat, lungs and ears. Many germs live in our bodies or are common in our surroundings. A healthy immune system can fight them off or keep them under control. However, HIV infection can weaken the immune system. Infections that take advantage of weakened immune defenses are called "opportunistic infections." People with advanced HIV disease can get opportunistic infections. See Fact Sheet 500 for more information on Opportunistic Infections."
New Mexico AIDS InfoNet
PO Box 810
Arroyo Seco, NM 87514
hivcc@nmia.com
http://www.aidsinfonet.org/articles.php?articleID=532

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Clarithromycin, Indications, RXlist.com:"Pharyngitis/Tonsillitis due to Streptococcus pyogenes (The usual drug of choice in the treatment and prevention of streptococcal infections and the prophylaxis of rheumatic fever is penicillin administered by either the intramuscular or the oral route. Clarithromycin is generally effective in the eradication of S. pyrogenes from the nasopharynx; however, data establishing the efficacy of clarithromycin in the subsequent prevention of rheumatic fever are not available at present.) Acute maxillary sinusitis due to Haemophilus influenzae, Moraxella catarrhalis, or Streptococcus pneumoniae. Acute bacterial exacerbation of chronic bronchitis due to Haemophilus influenzae, Moraxella catarrhalis, or Streptococcus pneumoniae."
http://www.rxlist.com/cgi/generic/clarith_ids.htm

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