A to Z Nursing Topics

Gatifloxacin(Tequin), Tequin Facts, Tequin.com:"Tequin® (gatifloxacin), a broad-spectrum 8-methoxy fluoroquinolone antibiotic, has been approved by the U.S. Food and Drug Administration for the safe and effective treatment of respiratory tract infections in adults 18 years or older, such as acute bacterial exacerbation of chronic bronchitis (ABECB), acute sinusitis and community-acquired pneumonia (CAP) caused by indicated susceptible strains of gram-positive and gram-negative bacteria."
http://www.tequin.com/tequin/home/index.jsp?BV_UseBVCookie=Yes

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Gatofloxacin, Clinical Pharmacology, RXlist:"The mechanism of action of fluoroquinolones including gatifloxacin is different from that of penicillins, cephalosporins, aminoglycosides, macrolides, and tetracyclines. Therefore, fluoroquinolones may be active against pathogens that are resistant to these antibiotics. There is no cross-resistance between gatifloxacin and the mentioned classes of antibiotics."
http://www.rxlist.com/cgi/generic3/gatifloxacin_cp.htm

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Gatifloxacin, Uses, Skidmore's Nursing Drug Updates:"Infection caused by susceptible Escherichia coli, Staphylococcus aureus, Haemophilus influenzae, H. parainfluenzae, Klebsiella pneumoniae, Moraxella catarrhalis, Neisseria gonorrhoeae, Proteus mirabilis, and other microorganisms: Chlamydia pneumoniae, Legionella pneumophila, Mycoplasma pneumoniae, acute bacterial exacerbation of chronic bronchitis, acute sinusitis, community-acquired pneumonia, gonorrhea."
http://www.us.elsevierhealth.com/MERLIN/nursingdrugupdates/Skidmore/archive/gatifloxacin.html

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Gatifloxacin(Tequin), Most important fact about this drug, PDR.net:"Quinolone antibiotics can cause serious and sometimes fatal allergic reactions, sometimes after a single dose. Stop taking this drug and call your doctor immediately if you develop swelling in the tongue, throat, or face; difficulty breathing or swallowing; itching, tingling; rash; hives; rapid or irregular heartbeat; seizures; or any other sign of an allergic reaction."
http://www.gettingwell.com/drug_info/rxdrugprofiles/drugs/TEQ1548.shtml

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Gatifloxacin, About your treatment, MEDLINEplus:"Your doctor has ordered gatifloxacin, an antibiotic, to help treat your infection. The drug will be added to an intravenous fluid that will drip through a needle or catheter placed in your vein for at least 60 minutes, once a day. Gatifloxacin is in a class of drugs called quinolone antibiotics. It eliminates bacteria that cause many infections, such as pneumonia and bronchitis; sinus, respiratory tract, and urinary tract infections; and sexually transmitted diseases."
http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a601238.html

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Gatifloxacin, Gatifloxacin Equal to Co-amoxiclav for Acute Sinusitis, May 11, 2000, Doctor's Guide:"The new once-daily fluoroquinolone, gatifloxacin, has been proved to be as effective as a three-times daily course of co-amoxiclav (amoxycillin 500 mg plus clavulanic acid 125 mg) for the treatment of acute sinusitis. Gatifloxacin is licensed in the US by Bristol-Myers Squibb, where it has been recently launched for the treatment of respiratory tract infections. Gatifloxacin is administered at a dose of 400 mg once daily for five to ten days depending upon the severity of the infection."
http://www.pslgroup.com/dg/1d159a.htm

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Gatifloxacin(Tequin), Side Effects, Health Square:"More common side effects may include: Diarrhea, dizziness, headache, nausea, stomach pain, vaginal inflammation, vomiting. Less common or rare side effects may include: Abdominal pain, abnormal dreams, abnormal thinking, acute allergic reaction, agitation or hostility, alcohol intolerance, allergic reaction, anxiety, arthritis, asthma, back pain, bad breath, blood in urine, bleeding in rectum, bluish skin, bone pain, breast pain, changes in thinking and perceptions, chest pain, chills, confusion, constipation, convulsion, depression, diabetes, difficulty breathing."
http://www.healthsquare.com/newrx/teq1548.htm

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Gatifloxacin, Range and Frequency, Whole Health MD:"For most infections: 400 mg once a day for 7 to 10 days. For community-acquired pneumonia: 400 mg a day for 7 to 14 days. For uncomplicated urinary tract infections: 400 mg as a one-time dose or 200 mg once a day for 3 days. For gonorrhea: 400 mg as a one-time dose. For those with impaired kidney function: Your doctor will determine the appropriate dosage."
http://www.wholehealthmd.com/refshelf/drugs_view/0,1524,891,00.html

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Gatifloxacin, New Study Shows Gatifloxacin to be An Effective and Well-Tolerated Treatment For Community-Acquired Pneumonia; In Comparison Test, Gatifloxacin Shows Edge Over Clarithromycin, September 29, 1999, PRnewswire.com:"The results of a multicenter Phase III study comparing the efficacy and safety of gatifloxacin to clarithromycin in treating community-acquired pneumonia (CAP) showed gatifloxacin to be more effective. The study findings were presented this week at the 39th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC). "
http://www.aegis.com/news/pr/1999/PR990971.html

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Gatifloxacin, Use cautiously in, Drug Guide.com:"Underlying CNS pathology, Renal impairment (dosage reduction if CCr £40 ml/min), Concurrent use of bepridil, cisapride, erythromycin, pentamidine, phenothiazines, or tricyclic antidepressants (may increase the risk of adverse cardiovascular reactions), Cirrhosis, Geriatric patients, dialysis patients (increased risk of adverse reactions), Lactation (safety not established). http://www.drugguide.com/extras/gatifloxacin.htm

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