Nursing & Healthcare Directories on: The Nursefriendly
Hyperlipedemics, Cholesterol Lowering, Medications,
Pravachol, (pravastatin sodium)

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Related Topics: Antihyperlipidemics, Cardiac Medications, Cholesterol Lowering Drugs, Coronary Artery Bypass Grafting, Diet Pills, Hyperlipidemia (High Cholesterol)

Related Drugs: Advicor, Baycol, Cerivistatin, Lescol, Fluvastatin, Lipitor, Pravachol, Pravastatin, Tricor, Fenofibrate, Zocor, Simvastatin

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Pravastatin(Pravachol), Pravachol.com:"Pravachol (pravastatin sodium) is prescribed for people with high cholesterol or heart disease along with diet, when diet and exercise are not enough. In some people, cholesterol cannot be controlled by diet and exercise alone. Clinical studies have shown that it not only reduces high cholesterol, but it is also the only statin proven to reduce the risk of first and second heart attack. It can benefit people who need to take a cholesterol-lowering medicine and for whom dietary change and exercise have not established healthy levels."
http://www.pravachol.com/

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Pravastatin (Pravachol), American Academy of Family Physicians:"The authors conclude that pravastatin provides a modest benefit in prevention of stroke among patients with known coronary artery disease. Treatment did not make a difference in rates of mortality related to stroke. However, the study did find a 24 percent relative reduction in the risk of death related to coronary artery disease and a 22 percent relative risk reduction in death from all causes, which were the primary end points of the first part of this trial."
http://www.aafp.org/afp/20010215/tips/6.html

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Pravastatin, Bristol Meyers Squibb:"Introduced more than ten years ago, pravastatin has been prescribed for millions of patients world wide. Pravachol® is the most widely studied statin medication, and more than 110,000 patients have been the subject of a number of clinical studies including:"
http://www.bms.se/heart_lakare/pravachol.htm

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Pravachol, Drugstore.com:"This medicine is an HMG-CoA reductase inhibitor (also known as a "statin") used to lower cholesterol and triglyceride levels in your blood. It may also be used to treat other conditions as determined by your doctor."
http://www.drugstore.com/pharmacy/prices/drugprice.asp?ndc=00003519510&trx=1Z5006

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Pravaststin(Pravachol), Annals of Internal Medicine:" In older patients with myocardial infarction and cholesterol levels in the average range, pravastatin is associated with a clinically important reduction in risk for major coronary events and stroke. Given the high cardiovascular event rate in older patients, the potential for absolute benefit in this age group is substantial."
http://www.acponline.org/journals/annals/01nov98/pravast.htm

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Pravaststin(Pravachol),Doctor's Guide:"People with high cholesterol can rapidly reduce their risk of having a first-time heart attack by 31 percent and their risk of death by 22 percent, by taking a widely prescribed drug called pravastatin sodium. This is the conclusion of a landmark study presented here today at the annual meeting of the American Heart Association. The results appear in the November 16, 1995, edition of the New England Journal of Medicine."
http://www.pslgroup.com/dg951116a.htm

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Pravaststin (Pravachol), Focus on Cholesterol:"Pravastatin is a cholesterol- lowering medicine. It inhibits the production of cholesterol by the liver. It lowers overall blood cholesterol as well as blood LDL cholesterol levels. LDL cholesterol is believed to be the "bad" cholesterol that is primarily responsible for the development of coronary artery disease. Lowering LDL cholesterol levels retards progression and may even reverse coronary artery disease, reducing the chance of heart attacks."
http://www.focusoncholesterol.com/script/main/Art.asp?li=MNI&ArticleKey=808

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Pravachol, Most important fact about this drug, Healthwell:"Pravachol is usually prescribed only if diet, exercise, and weight-loss fail to bring your cholesterol levels under control. It's important to remember that Pravachol is a supplement—not a substitute—for those other measures. To get the full benefit of the medication, you need to stick to the diet and exercise program prescribed by your doctor. All these efforts to keep your cholesterol levels normal are important because together they may lower your risk of heart disease."
http://www.healthsquare.com/newrx/PRA1344.HTM

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Pravastatin, Interactions with Dietary Supplements, Healthwell:"Pravastatin is a member of the HMG-CoA reductase inhibitor family of drugs, also called “statins,” such as lovastatin and simvastatin. Pravastatin blocks a key step in the body’s production of cholesterol and is used to lower cholesterol levels in people with hypercholesterolemia (high cholesterol)."
New Hope Natural Media
1401 Pearl Street
Boulder, CO 80302
303-939-8440
http://www.healthwell.com/healthnotes/healthnotes.cfm?ContentID=1466000

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Pravachol, What special dietary instructions should I follow? Medline Plus:"Eat a low-cholesterol, low-fat diet. This kind of diet includes cottage cheese, fat-free milk, fish (not canned in oil), vegetables, poultry, egg whites, and polyunsaturated oils and margarines (corn, safflower, canola, and soybean oils). Avoid foods with excess fat in them such as meat (especially liver and fatty meat), egg yolks, whole milk, cream, butter, shortening, lard, pastries, cakes, cookies, gravy, peanut butter, chocolate, olives, potato chips, coconut, cheese (other than cottage cheese), coconut oil, palm oil, and fried foods."
http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a692025.html

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Pravaststin (Pravachol), Mosby's Drug Consult:"The recommended starting dose is 10 or 20 mg once daily at bedtime. In primary hypercholesterolemic patients with a history of significant renal or hepatic dysfunction, and in the elderly, a starting dose of 10 mg daily at bedtime is recommended. Pravastatin may be taken without regard to meals."
http://www.mosbysdrugconsult.com/DrugConsult/Top_200/Drugs/e3064.htm

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Pravaststin(Pravachol), Powernet Designs:" Grapefruit juice had no effect on the pharmacokinctics of pravastatin. Concomitant use of atorvastatin and at least large amounts of grapefruit juice should be avoided, or the dose of atorvastatin should be reduced accordingly. (Clin. Pharmacol Ther 1999;66:118-27.)"
http://www.powernetdesign.com/grapefruit/references/ref52abstract.html

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Pravastatin(Pravachol), Rxlist:"Therapy with lipid-altering agents should be considered a component of multiple risk factor intervention in those individuals at increased risk for atherosclerotic vascular disease due to hypercholesterolemia. Lipid-altering agents should be used in addition to a diet restricted in saturated fat and cholesterol when the response to diet and other nonpharmacological measures alone has been inadequate ."
http://www.rxlist.com/cgi/generic/pravast_ids.htm

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Pravastatin(Pravachol),Heartcenter Online:"Jan 21 (Reuters Health) - A US Food and Drug Administration (FDA) advisory committee voted 7-1, with one abstention, against approval of the Bristol-Myers Squibb's Pravachol (pravastatin) and aspirin combination for patients with high cholesterol who have had a heart attack or other cardiac event."
http://www.heartcenteronline.com/myheartdr/home/research-detail.cfm?reutersid=2258&nl=1

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Last updated by Andrew Lopez, RN on Monday, November 22, 2010


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