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Gabapentin(Neurontin), General Information, Center Watch:"Neurontin® (gabapentin) is an anticonvulsant used to control various types of seizures in the treatment of epilepsy. It has also been used with some success in other conditions, including post poliomyelitis pain and amyotrophic lateral sclerosis. It was recently approved as an adjunctive therapy (added to other antiepileptic drugs) for the treatment of partial seizures in pediatric patients, and was previously approved for the treatment of partial seizures with and without secondary generalization in adults with epilepsy." http://www.centerwatch.com/patient/drugs/dru652.html ******************************************************
Gabapentin(Neurontin), Neurontin in the management of pain, Neuroland:"Neurontin is currently indicated as an adjunctive therapy in the treatment of partial onset seizures in adults." ******************************************************
Gabapentin(Neurontin), Why is this drug prescribed, Health Square:" Neurontin, an epilepsy medication, is used with other medications to treat partial seizures (the type in which symptoms are limited). It may be prescribed whether or not the seizures eventually become general and result in loss of consciousness." ******************************************************
Gabapentin(Neurontin), RXlist.com:Gabapentin is indicated as adjunctive therapy in the treatment of partial seizures with and without secondary generalization in adults with epilepsy." ******************************************************
Gabapentin, Indications, RXlist:"Gabapentin is indicated as adjunctive therapy in the treatment of partial seizures with and without secondary generalization in adults with epilepsy." ******************************************************
Gabapentin(Neurontin),Psychom.net:"Gabapentin has had been successful in controlling rapid cycling and mixed bipolar states in some people who have not received adequate relief from carbamazepine and/or valproate. It also appears that gabapentin has significantly more antianxiety and antiagitation potency than either carbamazepine or valproate. Gabapoentin has also been shown to be useful as a treatoent for antipsychotic-induced tardive dyskinesia." ******************************************************
Gabapentin(Neurontin),priory.com:"For epileptic control: Titration of dose to 900 - 1200mg daily in divided doses; 300mg once a day on day 1; 300mg twice a day on day 2; and 300mg three times a day on day 3. On day ,4 the dose may be increased to 1 200mg given in three equally divided doses. If necessary, further titration can occur using increments of 300mg per day given in three equally divided doses up to a maximum of 2400mg/day. It is not necessary to rnonitor gabapentin plasma concentrations to optimize gabapentin therapy. If there is a need for dose reduction, discontinuation or substitution of an alternative anticonvulsant, this should be done gradually over a minimum of one week." ******************************************************
Gabapentin(Neurontin),Medicine Net:"Gabapentin appears to be relatively safe and has not been shown to interact with other drugs except for it's potential of added sedation. Gabapentin should not be taken within 2 hours of Maalox. Gabapentin may interfere with the reading of N- Multistix in detecting urine protein." ******************************************************
Gabapentin(Neurontin),aafp:"Gabapentin is well absorbed orally, circulates mostly unbound in the plasma and is excreted unchanged in the kidneys without appreciable metabolism in the body. Oral bioavailability is approximately 60 percent and is not affected by food. The half-life is five to seven hours and is related to the creatinine clearance. Therefore, excretion is decreased in patients with renal impairment and decreased cardiac function, and in elderly patients.1 Gabapentin can be removed from the system through hemodialysis." ******************************************************
Gabapentin(Neurontin),National MS Society:"This medicine will add to the effects of alcohol and other central nervous system depressants that may cause drowsiness (e.g., antihistamines, sedatives, tranquilizers, prescription pain medications, seizure medications, muscle relaxants)." ******************************************************
Gabapentin(Neurontin),Doctor's Guide:"MADISON, WI -- Dec. 1, 1998 -- A new study led by researchers from the University of Wisconsin Medical School has found that a medication now used for controlling seizures is also effective against the pain of diabetic neuropathy -- and produces fewer and less serious side effects than currently available treatments. Gabapentin, an anti-convulsant available in the U.S. for four years, not only significantly reduced pain from chronic neuropathy (due to damaged nerves) but also reduced sleep disturbances, improved mood and enhanced patients’ quality of life." ******************************************************
Gabapentin(Neurontin), Neurontin Significantly Reduces Chronic Neuropathic Pain, December 23, 1998, Doctor's Guide:"Two studies recently published in The Journal of the American Medical Association, report that Parke-Davis' Neurontin(R) (gabapentin capsules) significantly reduced chronic neuropathic pain." ******************************************************
Gabapentin(Neurontin),Headachepainfree.com:"WESTPORT, CT (Reuters Health) Mar 30 - Gabapentin (Neurontin) at 2400 mg/day is an effective prophylactic agent for patients with migraine headaches, according to results of a multicenter trial." ******************************************************
Gabapentin(Neurontin), What are its applications, Epilepsy Foundation of Victoria:"Trials have shown that Gabapentin is effective in controlling epilepsy for some people, particularly those with complex partial and secondarily generalised partial seizures. It is usually added on to tablets that people are already taking rather than used by itself." ******************************************************
Gabapentin, Description, MEDLINEplus:"Gabapentin (GA-ba-pen-tin) is used to help control some types of seizures in the treatment of epilepsy. This medicine cannot cure epilepsy and will only work to control seizures for as long as you continue to take it." ******************************************************
Gabapentin(Neurontin), Health Library, Laurus Health:"Gabapentin is a drug used to treat or prevent seizures in people with seizure disorders." ******************************************************
Gabapentin, Pain Lessons,University Center for Pain Medicine and Rehabilitation at Memorial Hermann:"Pain physicians began using gabapentin soon after its release as an alternative to carbamazepine, phenytoin and valproic acid, all of which are more toxic. News of its efficacy in certain neuropathic pain disorders spread rapidly. A recent poster displayed at the American Pain Society meeting described its use in 10 patients with neuropathic pain ranging in duration from 10 months to 6 years. Pain relief in all patients was more than 75 percent."
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