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Allegra-D, (fexofenadine/pseudoephedrine)
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Allegra, Manufacturer's Home Page:"Allegra is a seasonal allergy medicine that your doctor can prescribe if it is right for you. Its active ingredient - fexofenadine - leaves you without the drowsiness which can be caused by many antihistamines. Studies show drowsiness in people who took Allegra was similar to those who took a sugar pill placebo. Allegra is a product of Aventis Pharmaceuticals. In keeping with its motto - Our Challenge is Life - our mission is curing disease one person at a time."
http://www.allegra.com/

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Allegra-D Prescribing Information - Aventis Pharmaceuticals:"Fexofenadine hydrochloride, the major active metabolite of terfenadine, is an antihistamine with selective peripheral H1-receptor antagonist activity. Fexofenadine hydrochloride inhibited antigen-induced bronchospasm in sensitized guinea pigs and histamine release from peritoneal mast cells in rats. In laboratory animals, no anticholinergic or alpha1-adrenergic-receptor blocking effects were observed. Moreover, no sedative or other central nervous system effects were observed. Radiolabeled tissue distribution studies in rats indicated that fexofenadine does not cross the blood-brain barrier."
http://www.aventispharma-us.com/PIs/allegra_d_TXT.html

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Allegra, Centerwatch.com: Allegra (fexofenadine hydrochloride),Newly Approved Drug Therapies:"Allegra has been approved as a treatment for seasonal allergic rhinitis. The labeling of Allegra recommends dosing of one 60-mg capsule, twice daily. The recommended starting dose for subjects with decreased kidney function is 60 mg, once daily. Allegra is available by prescription only."
http://www.centerwatch.com/drugs/DRU157.HTM

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Allegra-D Available In Time For Allergy Season, Doctor's Guide:"New relief for seasonal allergy sufferers with nasal congestion is being made available just in time for allergy season. Hoechst Marion Roussel’s Allegra-D(TM) (fexofenadine hydrochloride 60 mg and pseudoephedrine hydrochloride 120 mg) Extended-Release Tablets, a non-sedating antihistamine with decongestant, is now obtainable by prescription in the United States."
http://www.pslgroup.com/dg/6168e.htm

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Most important fact about this drug, Allegra D, PDRhealth.com:"Seldane, an antihistamine related to Allegra, has been implicated in dangerous interactions with the common antibiotic erythromycin, the antifungal medication ketoconazole (Nizoral), and several similar drugs. Allegra poses no such risks. It is also safe for people with liver disease."
http://www.gettingwell.com/drug_info/rxdrugprofiles/drugs/all1013.shtml

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Allegra D, Rxlist.com:"Patients taking Fexofenadine HCl; Pseudoephedrine HCl tablets should receive the following information: Fexofenadine HCl; Pseudoephedrine HCl tablets are prescribed for the relief of symptoms of seasonal allergic rhinitis. Patients should be instructed to take Fexofenadine HCl; Pseudoephedrine HCl tablets only as prescribed. Do not exceed the recommended dose. If nervousness, dizziness, or sleeplessness occur, discontinue use and consult the doctor. Patients should also be advised against the concurrent use of fexofenadine HCl; pseudoephedrine HCl tablets with over-the-counter antihistamines and decongestants."
http://www.rxlist.com/cgi/generic3/fexpseph_pi.htm

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Send comments and mail to Andrew Lopez, RN

Created on April 26, 1999

Last updated by Andrew Lopez, RN on Monday, November 22, 2010


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